On the blockage problem and the non-analyticity of the current for the parallel TASEP on a ring

The Totally Asymmetric Simple Exclusion Process (TASEP) is an important example of a particle system driven by an irreversible Markov chain. In this paper we give a simple yet rigorous derivation of the chain stationary measure in the case of parallel updating rule. In this parallel framework we then consider the blockage problem (aka slow bond problem). We find the exact expression of the current for an arbitrary blockage intensity $\varepsilon$ in the case of the so-called rule-184 cellular automaton, i.e. a parallel TASEP where at each step all particles free-to-move are actually moved. Finally, we investigate through numerical experiments the conjecture that for parallel updates other than rule-184 the current may be non-analytic in the blockage intensity around the value $\varepsilon = 0$

Do Consumers Want More Nutritional and Health Information on Wine Labels? Insights from the EU and USA

The global strategy to reduce the harmful use of alcohol launched in 2010 by the World Health Organization includes, amongst several areas of recommended actions, providing consumer information about, and labelling, alcoholic beverages to indicate alcohol-related harm. Labelling requirements worldwide for alcoholic drinks are currently quite diverse and somewhat limited compared to labelling on food products and on tobacco. In this context, the current paper contributes to the academic and political debate on the inclusion of nutritional and health information on wine labelling, providing some insights into consumer interest in, and preferences for, such information in four core wine-producing and -consuming countries: Italy, France, Spain, and the United States of America. A rating-based conjoint analysis was performed in order to ascertain consumer preferences for different formats of additional information on wine labels, and a segmentation of the sample was performed to determine the existence of homogeneous groups of consumers in relation to the degrees of usefulness attached to the nutritional and health information on wine labels. Our results highlight the interest expressed by European and United States consumers for introducing nutrition and health information on wine labels. However, the results of conjoint analysis show some signi\ufb01cant differences among stated preferences of the information delivery modes in different countries. In addition, segmentation analysis reveal the existence of signi\ufb01cant differences between consumer groups with respect to their interest in receiving additional information on wine labels. These differences are not only linked to the geographic origin of the consumers, or to socio-demographic variables, but are also related to wine consumption habits, attitudes towards nutritional information, and the degree of involvement with wine. This heterogeneity of consumer preferences indicates a need for a careful consideration of wine labelling regulations and merits further investigation in order to identify labelling guidelines in terms of the message content and presentation method to be used

Health warnings on wine labels: a discrete choice analysis of Italian and French Generation Y consumers

This paper aims to analyse Generation Y consumers' preferences for, interest in and attitudes towards different formats of health warnings on wine labels in two countries with different legal approaches: France and Italy. A Discrete Choice Experiment was realized on a sample of 500 wine consumers. Three warning options were applied: the long-term effect of drinking (brain damage); a short-term effect (car crash) and no warning option. Four attributes composed the choice set: alcohol content; framing of warning statement; warning size and position. Findings reveal that both the general degree of attention to the label and the level of visibility of the warnings are low, as are their effectiveness in changing consumption. Generation Y tend to prefer the ''no logo option'', short-term effects warnings and a small logo posted on the back label with neutrally framed messages. Results also show some significant differences among preferences in France and Italy, providing inputs to the ongoing debate in the EU on mandatory labelling. Although findings are subject to limitations related to the use of self-reported questionnaire and prone to social-desirability bias, practical implications are clear for private companies interested in implementing marketing strategies focused on enhancing the efficacy and readability of labels. Keywords: Health warning, Wine labelling, Discrete Choice Experimen

Non-Conventional Hybrid Microporous Layers for Enhanced Performance and Durability of PEM Fuel Cells

In this work, novel microporous layers (MPLs) were developed based on fluorinated ethylene propylene (FEP), as a hydrophobic agent, and carboxymethylcellulose (CMC), as a wettability modulator and rheology controller for the inks, which were deposited onto pre-hydrophobized macroporous gas diffusion layers (GDLs). Higher CMC amounts led to higher dynamic viscosities of the inks, which induced the formation of a more compact and less cracked MPL surface. Different concentrations of CMC were tested and the experimental measurements showed a threshold limit pointing out an optimal composition that positively affected the electrochemical performances at medium-low relative humidity (RH), which is important to mitigate the need of saturating inlet gases. Durability of the best performing samples was assessed by means of an ad hoc developed accelerated stress test (AST) and compared to one of the conventional FEP-based GDMs. It was found that a lower decrement of both the output power density and the overall cell efficiency can be obtained upon the ASTs with the novel samples

Toward an adjustable nonlinear low frequency acoustic absorber

International audienceThis paper presents experimental results showing that a loudspeaker used as a suspended piston working outside its range of linearity can also be used as a nonlinear acoustic absorber. The main advantage of this technology of absorber is the perspective to adjust independently the device parameters (mass, nonlinear stiffness and damping) according to the operational conditions. To achieve this purpose, quasi-static and dynamic tests have been performed on three types of commercial devices (one with structural modifications), in order to define the constructive characteristics that it should present. An experimental setup has been developed using a one-dimensional acoustic linear system coupled through a box (acting as a weak spring) to a loudspeaker used as a suspended piston acting as an essentially nonlinear oscillator. The tests carried out on the whole vibro-acoustic system have showed the occurrence of the acoustic TET from the acoustic media to the suspended piston and demonstrated the efficiency of this new kind of absorber at low frequencies over a wide frequency range. Moreover, the experimental analyses conducted with different NES masses have confirmed that it is possible to optimize the noise absorption with respect to the excitation level of the acoustic resonator

Niosomes for Topical Application of Antioxidant Molecules: Design and In Vitro Behavior

In the present study, gels based on xanthan gum and poloxamer 407 have been developed and characterized in order to convey natural antioxidant molecules included in niosomes. Specifically, the studies were conducted to evaluate how the vesicular systems affect the release of the active ingredient and which formulation is most suitable for cutaneous application. Niosomes, composed of Span 20 or Tween 20, were produced through the direct hydration method, and therefore, borate buffer or a micellar solution of poloxamer 188 was used as the aqueous phase. The niosomes were firstly characterized in terms of morphology, dimensional and encapsulation stability. Afterwards, gels based on poloxamer 407 or xanthan gum were compared in terms of spreadability and adhesiveness. It was found to have greater spreadability for gels based on poloxamer 407 and 100% adhesiveness for those based on xanthan gum. The in vitro diffusion of drugs studied using Franz cells associated with membranes of mixed cellulose esters showed that the use of a poloxamer micellar hydration phase determined a lower release as well as the use of Span 20. The thickened niosomes ensured controlled diffusion of the antioxidant molecules. Lastly, the in vivo irritation test confirmed the safeness of niosomal gels after cutaneous application

Similar rate of return to sports activity between posterior-stabilised and cruciate-retaining primary total knee arthroplasty in young and active patient

PURPOSE Cruciate-retaining and posterior-stabilised implant designs are available for primary total knee arthroplasty. However, whether the implant design is associated with a difference in the level of activity still remains unclear. This clinical trial compared posterior-stabilised and cruciate-retaining implants in sport-related patient-reported outcome measures, range of motion, rate of return to sport, and weekly time dedicated to sport in active adults. It was also hypothesised that in young and active patients both implants lead to a similar rate of return to sport in terms of hours per week, type of sport, and joint mobility. METHODS All patients were evaluated preoperatively and for a minimum of 36 months follow-up. The University of California Los Angeles activity scores, High-Activity Arthroplasty Score, and Visual Analogue Scale were administered preoperatively and at the last follow-up. The range of motion was investigated at admission and the last follow-up. Data concerning the hours per week dedicated to sports and the type of sport practiced were also collected at admission and at the last follow-up. The Kaplan-Meier Curve was performed to compare implant survivorship. RESULTS Data from 227 procedures (cruciate-retaining: 109, posterior-stabilised: 118) were prospectively collected. At the last follow-up, no difference was reported in The University of California Los Angeles activity scores (p = 0.6), High-Activity Arthroplasty Score (p = 0.1), Visual Analogue Scale (p = 0.9), flexion (p = 0.7) and extension (p = 0.4). No difference was found in the rate of return (p = 0.1) and weekly hours dedicated to sport (p = 0.3). The Kaplan-Meier curve evidenced no statistically significant difference in implant survivorship (p = 0.6). CONCLUSIONS At approximately five years of follow-up, no difference was reported between cruciate-retaining and posterior-stabilised implants in active adults in sport-related patient-reported outcomes measures, range of motion, pain, weekly time dedicated to sport, rate of return to sport, and implant survivorship. LEVEL OF EVIDENCE Level II, prospective study

Room-temperature synthesis of 2D-Ti3C2Tx nano-sheets by organic base treatment

The growing demand for improved electrochemical performance in energy storage systems has stimulated research into advanced two-dimensional (2D) materials for electrodes. In this work, we obtain a layered MXene compound by exfoliating a titanium aluminum carbide precursor using tetramethylammonium hydroxide (TMAOH) ions in a full room temperature process followed by manual shaking. The hexagonal crystal structure and composition of the layered materials are characterized using different techniques. X-Ray diffraction shows the formation of 2D nano-sheets before and after the TMAOH treatment via its characteristic (002) diffraction peak, bringing to light an increase in the interlayer spacing after treatment. Scanning electron microscopy images confirm the layered morphology, whose composition is determined by energy dispersive x-ray analysis for the bulk material and by x-ray photoelectron spectroscopy for the surface of the obtained compounds. This study demonstrates a promising route to enhance delamination of this MXene 2D material in a low-cost room-temperature approach

Image Test Libraries for the on-line self-test of functional units in GPUs running CNNs

The widespread use of artificial intelligence (AI)-based systems has raised several concerns about their deployment in safety-critical systems. Industry standards, such as ISO26262 for automotive, require detecting hardware faults during the mission of the device. Similarly, new standards are being released concerning the functional safety of AI systems (e.g., ISO/IEC CD TR 5469). Hardware solutions have been proposed for the in-field testing of the hardware executing AI applications; however, when used in applications such as Convolutional Neural Networks (CNNs) in image processing tasks, their usage may increase the hardware cost and affect the application performances. In this paper, for the very first time, a methodology to develop high-quality test images, to be interleaved with the normal inference process of the CNN application is proposed. An Image Test Library (ITL) is developed targeting the on-line test of GPU functional units. The proposed approach does not require changing the actual CNN (thus incurring in costly memory loading operations) since it is able to exploit the actual CNN structure. Experimental results show that a 6-image ITL is able to achieve about 95\% of stuck-at test coverage on the floating-point multipliers in a GPU. The obtained ITL requires a very low test application time, as well as a very low memory space for storing the test images and the golden test responses